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Obecny wzrost częstości występowania osteoporozy i złamań osteoporotycznych wśród mężczyzn oraz spadek wieku, w którym te pierwsze występują, rodzą pytanie o historyczne zmiany we wzorach utraty masy kostnej wraz z wiekiem, w tym o różnice międzypłciowe oraz ich biologiczne i kulturowe uwarunkowania w populacjach historycznych. Naukowcy z Katedry Antropologii, Pracowni Biobank oraz Katedry Chemii Organicznej Uniwersytetu Łódzkiego wraz z Zakładem Zaburzeń Endokrynnych i Metabolizmu Kostnego Uniwersytetu Medycznego, przy współpracy z Uniwersytetem of Adelaide z Australi  przeprowadzili badania mające okreslić wzorzec zmian gęstości mineralnej kości wśród mężczyzn na ziemiach polskich od neolitu do czasów nowożytnych. Wyniki zostały opublikowane w pracy „Osteoporotic bone fractures and age-related bone loss in males inhabiting the Kujawy region in north-central Poland from the Neolithic to early modern Times”, na łamach czasopisma Journal of Archaeological Science (IF= 3.061).  Zapraszamy do lektury.

 

 

Wiesław LorkiewiczaJoanna MietlińskaaJustyna KarkusaMarta KurekaPaulina Borówkaa,b

Michał Stussc,dEwa Sewerynekc,dDamian PlażukeElżbieta Żądzińskaa,f

 

aDepartment of Anthropology, Faculty of Biology and Environmental Protection, University of Łódź, Poland
bBiobank Laboratory, Faculty of Biology and Environmental Protection, University of Łódź, Poland
cDepartment of Endocrine Disorders and Bone Metabolism, Medical University of Łódź, Poland
dOutpatient Clinic of Osteoporosis, Regional Centre of Menopause and Osteoporosis, Military Medical Academy Memorial Teaching Hospital, The Medical University of Łódź, Central Veterans' Hospital, Łódź, Poland
eLaboratory of Molecular Spectroscopy, Department of Organic Chemistry, Faculty of Chemistry, University of Łódź, Poland
fVisiting Research Fellow in the School of Medical Sciences within the Faculty of Health Sciences, The University of Adelaide, South Australia, 5005, Australia

 

 

Abstract

The current increase in the incidence of osteoporosis and osteoporotic fractures among men and the decrease in age in which these first occur raise the question about historical changes in the patterns of bone loss with age, including sex differences, and their biological and cultural determinants in the past. The present study analyzed bone mineral density (BMD) and bone fractures in 267 male skeletons representing six geographically homogeneous populations from the region of Kujawy in north-central Poland, both prehistoric (Middle Neolithic) and historical (early Middle Ages to early modern times). Sex differences in BMD were investigated using data from a previous study of females from these populations (Spinek et al., 2016). In general, the regular patterns of age-related bone loss found in men from the studied archaeological populations were similar to those observed today. In all age groups, Neolithic men showed a significantly higher BMD as compared to the historical samples; on the other hand, the latter revealed similar values to contemporary populations in the middle and old age groups. Thus, in the analyzed period, a major transition in bone maintenance patterns occurred between the Neolithic and the Early Middle Ages. The archaeological populations exhibited a faster rate of bone loss with age: while their initial BMD levels were higher than those in contemporary populations, BMD for the oldest age groups was similar to or even lower than today. The most pronounced sex differences in BMD were found for young adults, which indicates a significantly greater influence of factors limiting peak bone mass and contributing to bone loss in young women, probably associated with reproductive history (age at menarche and pregnancies). The men, and especially young individuals, exhibited a higher prevalence of osteoporotic fractures as compared to the women. The main factor determining such sex- and age-specific patterns of osteoporotic fractures in the analyzed skeletal samples was the generally greater susceptibility to injuries of the males.